Alzheimer's protein + secretase model
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A multi-subunit print of Gamma secretase (surface representation) with in-place Amyloid Beta (Cartoon).
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Informacje o modelu
- Źródło
- Printables
- Kategoria
- Chemistry & Biology
- Licencja
- Creative Commons — Public Domain
Gamma Secretase is a multi-protein complex which is integrated in to the cell membrane. The complex cleaves other proteins which pass through the cell membrane, such as the Amyloid Precursor Protein (APP) which gives rise to Amyloid Beta, the major component of amyloid plaques found in the brain of Alzheimer's disease patients.
Prints with supports, 0.2 or 0.1mm and can be assembled/glued. Multiple components allows for multi-color prints, I opted for a cream print with just Amyloid Beta in red. The Nicastrin protein is printed in two parts (globule and transmembrane extension) with a square joint connecting them. The APH1-Nicastrin fit is tight, I had to clip APH1 prior to gluing.