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Pyruvate Dehydrogenase Core — image 1
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Pyruvate Dehydrogenase Core

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EDIT: Uploaded dodecahedral enzyme from Geobacillus stearothermophilus, 1b5s This is a complex which forms the…

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EDIT: Uploaded dodecahedral enzyme from Geobacillus stearothermophilus, 1b5s

This is a complex which forms the catalytic core of the pyruvate dehydrogenase multienzyme. The structure is made of 24 copies of a single protein; three copies make up each vertex of the cube. Pyruvate dehydrogenase is an enormous enzyme that connects the process of glycolysis, by which sugars are broken down, to the process of aerobic respiration.

This enzyme is actually from the bacterium Azotobacter vineladii; the human version of the enzyme forms a dodecahedron. Read more about it here http://www.rcsb.org/pdb/101/motm.do?momID=153

1eaa in the pdb.

Instructions

Print with support, I made this at 1/4 scale. I used KISSlicer, with the "dense" support option, and I also have a script which decreases the support flow rate to 70%

This was made with natural ABS on an ultimaker with a heated platform.

Category: Biology

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