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Educational model: Gas vesicle / scale 1:5,000,000 — image 1
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Educational model: Gas vesicle / scale 1:5,000,000

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3D model of a gas vesicle, a unique gas-filled protein assembly inside aquatic microorganisms that make them float.

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Model information

License
Creative Commons — Attribution — Noncommercial — NoDerivatives

The 3D model is based on data from our recent preprint:

Huber et. al, Cryo-EM structure of gas vesicles for buoyancy-controlled motility, BioRxiv (2022)

It consists of two identical half-shells made from 865 copies of the 7.5 kDa protein GvpA, 38 copies of the ~22 kDa protein GvpC attached on the outside and a stand. The half-shells can be moved against each other to illustrate our proposed mechanism of growth and monomer insertion. GvpC can be added by clipping it onto alpha-helix 2 of the GvpA monomer with little regularly spaced hooks corresponding to the 5x33AA repeats of GvpC.

The half-shells are cut in 3 parts for easier printing and have to be glued with e.g. epoxy glue.

Expect to take ~120 hours of printing and ~half a kilogram of filament, equal to ~10-15 Euro of printing costs.

I included files for a 50% scale model as well.

The .mmcif file of the 3D model is deposited on zenodo:

https://doi.org/10.5281/zenodo.6458345