Histidine (C6H9N3O2) - Multi-Color 3D Molecule Model

Histidine (C6H9N3O2) - Multi-Color 3D Molecular Model (Space-Filling Spheres)

An accurate, educational 3D printable model of Histidine (C6H9N3O2) in classic Space-Filling (van der Waals / CPK Spheres) style. Ideal for chemistry classrooms, students, researchers, science educators, or as a vibrant desk display.

Printed in a single piece using multi-material systems (Prusa MMU3, Bambu AMS, Toolchangers) — no gluing or assembly required!

Generated with the web tool 3D Print Molecules.

🧪 About the Molecule

Histidine is an essential amino acid bearing an aromatic imidazole ring with a near-neutral pKa.

• Chemical Formula: C6H9N3O2

• IUPAC / Common Name: Histidine

• Structure Coordinates: pubchem

💡 Did You Know?

Histidine is the body's ultimate 'molecular chameleon'—its imidazole ring shifts effortlessly between neutral and positively charged states at physiological pH (~6.0), making it the star catalytic player in dozens of enzyme active sites!

🌟 Real-World Uses & Fascinating Facts

• 🤧 Histamine & Allergies: Decarboxylation of histidine produces histamine, the master chemical mediator of allergic hives, seasonal rhinitis, and stomach acid secretion.

• 🥩 Muscle Endurance (Carnosine): Combines with beta-alanine to form carnosine, shielding hard-working muscle cells against fatigue-inducing lactic acidosis.

• ☀ Natural UV Shield: In the epidermis, histidine converts into urocanic acid, a natural biological sunscreen that absorbs damaging ultraviolet solar radiation.

🧠 Biological Role & Science Notes

Histidine residues coordinate iron in the heme pocket of hemoglobin and myoglobin, allowing reversible oxygen binding. It also coordinates catalytic zinc and copper ions in superoxide dismutase and metalloproteinases.

🔬 Scientific Precision

• van der Waals Radii: Proportions strictly match standard physical van der Waals radii (Bondi, 1964).

• Conformational Reality: Geometry reflects the lowest-energy real-world conformation derived from computational force fields (MMFF94) and crystallographic/quantum benchmarks.

• CPK Color Standard: Colors follow the classic international Corey-Pauling-Koltun (CPK) palette.

🚀 Why Use the 3D Print Molecules Web App? (3dmolekuly.vscht.cz)

This model was generated using our web visualizer designed to make multi-color 3D printing of molecules seamless:

• 🎯 Automatic Multi-Part Mesh for Multi-Color Printing: No manual cutting or CAD modeling required. The generator automatically isolates each chemical element into separate manifold bodies so PrusaSlicer, Bambu Studio, and OrcaSlicer immediately assign colors!

• 🔬 Authentic Space-Filling Volumes: Generates clean, manifold overlapping sphere volumes reflecting real molecular geometry.

• ⚙ Full Customization: Adjust atom diameters, mesh resolution, scale (mm/Å), and toggle hydrogen atoms on or off.

• 🎓 Free & Web-Based: Developed at the University of Chemistry and Technology, Prague (VŠCHT Praha). Free to use, runs right in your browser with zero installation.

(📸 Check the web app screenshot in the photos to view the model loaded in the visualizer with the settings panel!)

🖨 Multi-Material Printing Instructions

• Style: Space-Filling Spheres (CPK)

• Assembly: None! Printed in one solid piece with multi-material systems.

• Element Color Assignments:

• Carbon (C): Black / Dark Grey

• Hydrogen (H): White

• Oxygen (O): Red

• Nitrogen (N): Blue

• Recommended Layer Height: 0.16 mm (optimal for smooth sphere curves) – 0.20 mm

• Perimeters / Walls: 3

• Infill: 15% Gyroid

• Supports: Tree / Organic supports recommended (use PETG support interface on PLA for 0mm contact distance)

💡 Support Interface Trick for Flawless Spheres

When printing PLA with multi-material units (MMU3, AMS, Toolchanger): Set your Support Interface Material to PETG with Top Z distance = 0 mm. Because PLA and PETG do not bond to each other, the organic/tree supports detach effortlessly by hand with zero surface scarring, leaving the spherical atoms perfectly smooth!

🔗 Customize Your Model or Create Any Molecule!

Need different tolerances for your printer, larger/smaller atoms, or want to export another molecule entirely?

👉 Open and customize directly in the 3D Print Molecules App

Created with ❤ at the University of Chemistry and Technology, Prague (VŠCHT Praha) • 3dmolekuly.vscht.cz