Topoisomerase I enzyme-DNA complex
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Printable Topoisomerase I protein model with DNA
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Updated at source:
Model information
- Source
- Printables
- Category
- Chemistry & Biology
- License
- Creative Commons — Attribution
This 3D model represents Topoisomerase I bound to the its DNA substrate. This enzyme regulates DNA topology by introducing transient single-strand breaks in DNA. Through a catalytic tyrosine residue, the enzyme forms a covalent bond with one of the DNA backbones, allowing controlled rotation of the DNA strand to release supercoiling. After relaxation, the DNA is religated. This model highlights the molecular mechanism of DNA strand management and is intended for educational and scientific visualization or decoration.
Coloring:
Protein: red
DNA: white
Print information:
Printer: Prusa MK4S
Supports required: Yes !!! Organic!!!
Layer height: min. 0.2 mm recommended for nice quality
Print scale: mind. 2000 % recommended
Filament type: PLA
Infill percentage: 5%
Perimeters: 2
USE organic supports !!! --> won't work otherwise
print all parts separately like I did in the print files and assemble them afterwards